Vitro Develops Novel Stem Cell Technology for Use in
Treatment of Hearing Loss
October 2011
Vitro Diagnostics, Inc. (OTCQB: VODG), dba Vitro Biopharma, announced
development of technical advancements with application to treatment of
hearing loss in animals and human through commercialization of a variety of
stem cell products to prevent, reverse and restore hearing in cases of
hearing loss.
Hearing reduction or loss is estimated to affect approximately 22 to 36
million individuals globally. Effective treatments of this condition thus
represent a multi-billion dollar market that is expected to increase as the
population ages. Hearing loss or reduction can occur by several causes
including environmental exposure to excessive sound and it is commonly
associated with aging. This market is primarily served by providers of
digital and analog hearing aids. Digital devices provide improved hearing
enhancement to users at increased cost. A predominant cause of hearing loss
is presbycusis, a condition thought to result from degeneration of hair
cells and other structures in the inner ear that through signaling to the
auditory nerve, result in the auditory perceptions underlying hearing.
Vitro's therapeutic products include molecular compositions to promote,
maintain and restore inner ear hair cells and related structures together
with adult stem cell transplantation to restore hearing loss. Vitro's
intellectual property has application to hearing restoration and prevention
of hearing loss through a series of products envisioned to provide various
treatment options for hearing loss. Vitro's discoveries may lead to new
pharmaceutical agents that stimulate activation of native adult stem cells
to regenerate inner ear hair cells, together with other cells derived from
adult stem cells, without the necessity of stem cell transplantation.
Recombinant cytokines including erythropoietin and granulocyte colony
stimulating factor are now widely used for therapeutic activation of the
hematopoietic stem cell system for treatment of adverse effects of
chemotherapy and represent major products of the biotechnology industry.
Vitro has developed other proprietary technology related to stem cell
products and technology with broad application to various areas in medical
research and therapy. Modern stem cell technology is rapidly evolving and
holds promise to revolutionize medicine by allowing replacement of any type
of cell within the human body. Diseases characterized by cellular
degeneration, including Alzheimer's disease, cardiovascular disease, heart
attack, stroke, diabetes, spinal cord injury, acute and chronic kidney
failure, hearing loss, macular degeneration and several other disorders may
be treatable through the development and further commercialization of stem
cell technology.
While the research and use of human embryonic stem cells is highly
contentious and ethically controversial, Vitro's stem cell technology is
based on adult human stem cells that are derived without sacrifice of
embryos needed to generate embryonic stem cells. Transplantation of adult
stem cells, derived from various tissues including bone marrow, has been
used for the past fifty years to treat leukemia, lymphoma and other blood
disorders and is now a widely available treatment option for several forms
of blood cancer and autoimmune diseases. New developments in stem cell
technology, including Vitro's patent-pending technology, are leading the way
to novel technologies using adult stem cells to provide the benefits of
embryonic stem cells including the ability to differentiate into any cell of
the body. This occurs through reprogramming of adult cells to become
functionally equivalent to embryonic stem cells. Such technology eliminates
the basis of the current ethical, religious and political issues associated
with the use of embryonic stem cells while capturing their clinical
advantages. The Company is seeking appropriate partnerships to commercialize
its stem cell products related to treatment of hearing loss.
About Vitro Diagnostics, Inc.
Vitro Diagnostics, Inc. dba Vitro Biopharma (OTCQB: VODG; http://www.vitrobiopharma.com),
owns US patents for production of FSH, immortalization of pituitary cells,
and a cell line that produces beta islets for use in treatment of diabetes.
Vitro also owns a pending international patent for generation of pluripotent
stem cells. Vitro's mission is "Harnessing the Power of Cells(tm)" for the
advancement of regenerative medicine to its full potential. Vitro operates
within a modern biotechnology manufacturing, R&D and corporate facility in
Golden, Colorado. Vitro manufactures and sells "Tools for Stem Cell and Drug
Development(tm)", including human mesenchymal stem cells and derivatives,
optimized media for stem cell self-renewal and lineage-specific
differentiation. Vitro recently formed a strategic alliance withHemoGenix(r),
Inc. (http://www.hemogenix.com/) to jointly manufacture and distribute
LUMENESC(tm)and LumiSTEM(tm) quantitative assays for determination of stem
cell quality, potency and response to toxic agents.
Safe Harbor Statement
Certain statements contained herein and subsequent statements made by and
on behalf of the Company, whether oral or written may contain
"forward-looking statements" within the meaning of the Private Securities
Litigation Reform Act of 1995. Such forward looking statements are
identified by words such as "intends," "anticipates," "believes," "expects"
and "hopes" and include, without limitation, statements regarding the
Company's plan of business operations, product research and development
activities, potential contractual arrangements, receipt of working capital,
anticipated revenues and related expenditures. Factors that could cause
actual results to differ materially include, among others, acceptability of
the Company's products in the market place, general economic conditions,
receipt of additional working capital, the overall state of the
biotechnology industry and other factors set forth in the Company's filings
with the Securities and Exchange Commission. Most of these factors are
outside the control of the Company. Investors are cautioned not to put undue
reliance on forward-looking statements. Except as otherwise required by
applicable securities statutes or regulations, the Company disclaims any
intent or obligation to update publicly these forward looking statements,
whether as a result of new information, future events or otherwise.
Source: Vitro Diagnostics, Inc.